I just "reviewed" a new user question that was obviously spam, so I flagged it as such during the review. That's one of the reasons why the new uers review process is in place, right?
But the question already had a score of -6 (so at least 6 downvotes). That implies there were 6 people willing to give away 1 point of their reputation. I'd hope they also flagged the question as spam, which I believe is a much more powerful feature.
My (related) questions:
even if you only "loose" like 1 point to downvote, and assuming that you're not on any SE site for "just the reputation" (that would be sad), why would you even give 1 such point of yours to that annoying spam question?
after such question gets deleted, do the downvoters get there -1 reputation corrected again (ie: does the delete cause something like an undo of the -1)?